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For example, in case your doctor prescribed it for 10 days, take it for your entire time.
At the same time the ratio of the serum concentrations of clarithromycin and its 14-OH metabolite was reversed from 3.3:1 to 1:2.7. There have been comparable, although less marked, adjustments after the addition of rifabutin 600 mg/day to a regimen that included clarithromycin one thousand mg/day.
There have been no serious hostile events. There was some dispute as to whether toxicity was dose-associated or not, but it is wise to advocate that elderly patients should obtain an initial day by day dose of 1 g in this disease setting. Progressive loss of strength and issue in swallowing and eye opening after the primary dose of clarithromycin (2 g/day) occurred in a patient with cerebral toxoplasmosis and AIDS.
Two patients (aged 21 and 33 years) with late-stage AIDS had acute psychoses shortly after taking clarithromycin (2 g/day) for MAC bacteremia. Remedy regimens for patients with a positive tradition for MAC from a sterile site should include two or extra drugs, including clarithromycin.